Grey's Anatomy - S4E1

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A Change is Gonna Come

Series 4, episode 1

Written by Shonda Rhimes

Directed by Rob Corn

Originally Aired On: Thursday, 27 September 2007

New series of the medical drama. Meredith, Cristina, Izzie and Alex spend their first day as residents with their own interns, including George, repeating his internship after failing his exams, and Meredith's half-sister. Cristina searches for Burke, who is nowhere to be found. Richard resumes his position as chief of surgery.

Cast

Image for Ellen PompeoEllen PompeoDr. Meredith Grey
Image for Sandra OhSandra OhDr. Cristina Yang
Image for Katherine HeiglKatherine HeiglDr. Isobel 'Izzie' Stevens
Image for Justin ChambersJustin ChambersDr. Alex Karev
Image for T.R. KnightT.R. KnightDr. George O'Malley
Image for Chandra WilsonChandra WilsonDr. Miranda Bailey
Image for James Pickens Jr.James Pickens Jr.Dr. Richard Webber
Image for Sara RamirezSara RamirezDr. Callie Torres
Image for Eric DaneEric DaneDr. Mark Sloan
Chyler LeighDr. Lexie Grey
Image for Patrick DempseyPatrick DempseyDr. Derek Shepherd
Image for Mark PellegrinoMark PellegrinoChris
Sandra ThigpenClara
Stephanie ChildersNancy Walters
Steven M. PorterJoey
Candice AfiaIntern Laura
Amrapali AmbegaokarIntern Dani
Tymberlee HillIntern Claire
Gloria GarayuaIntern Graziella
Molly KidderIntern Megan
Richard KeithIntern Mitch
Joy OsmanskiIntern Lucy
Winston StoryIntern Leo
Joseph WilliamsonIntern Pierce
Ariel FelixAnesthesiologist
Terrance Christopher JonesParamedic
John CapponParamedic
Mac BrandtParamedic
Jaden SorensenMichael
Terrence FlackHenry Flynn
Nadji JeterBobby
Na'Kia Bell SmithTina
Na'Kia Bell SmithTina